Spondyloarthritis & psoriatic arthritis
Global Functioning in Axial Spondyloarthritis is Stronger Associated With Disease Activity and Function Than With Mobility and Radiographic Damage
Authors' conclusion
This study shows that axSpA disease-specific PROs have an impact on global functioning, whereas spinal mobility scores, even if objectively assessed by the ES, have limited impact on patient reported-global functioning. The results also suggest that global functioning is, in this cohort, not much dependent on the degree of structural damage in the axial skeleton.
Study context
- Population
- Consecutive patients with radiographic and nonradiographic axial spondyloarthritis (axSpA)
- Participants
- 103 patients
- Outcome
- Correlation of global functioning (ASAS HI) with disease activity, physical function, spinal mobility and radiographic damage
Methodological detailsconsecutive patients, Kendall's tau correlation
- Consecutive patients
- Kendall's tau correlation
Main finding
As reported in the abstract
Correlation (Kendall's tau) of ASAS HI with clinical measures
- ASAS HI vs BASDAI, r
- 0.36 (P < 0.001)
- ASAS HI vs Bath AS functional index (BASFI), r
- 0.48 (P < 0.001)
- ASAS HI vs back pain, r
- 0.41 (P < 0.001)
- ASAS HI vs range of motion (RoM) and range of kinematics (RoK) (Epionics SPINE), r (no significant correlation)
- between −0.08 and 0.09
- ASAS HI vs radiographic damage in SIJ and spine, r (no significant correlation)
- between 0.03 and 0.004
- ASAS HI vs Bath AS metrology index (BASMI), r (weak)
- 0.14 (P = 0.05)
Observational data: associations, not effects.
Original publication
Global Functioning in Axial Spondyloarthritis is Stronger Associated With Disease Activity and Function Than With Mobility and Radiographic Damage. Arthritis Care Res (Hoboken). Published 4 October 2023. doi:10.
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