Pediatric rheumatology

Evaluation of epicardial adipose tissue thickness and carotid intima-media thickness in children with Behçet's disease

Clin Exp RheumatolPublished Cross-sectional study

Authors' conclusion

The EAT thickness was found to be significantly higher in paediatric BD patients.

Study context

Population
Children with juvenile-onset behçet's disease (BD), all inactive at evaluation, and age-sex-matched healthy controls
Participants
30 vs 20
Exposure
Juvenile-onset BD vs age-sex-matched healthy controls
  • BDn = 30
  • Healthy controlsn = 20reference
Outcome
EAT thickness and CIMT
Methodological detailsage-sex-matched healthy controls, single paediatric cardiologist measurements, carotid intima-media thickness (CIMT) and epicardial adipose tissue (EAT) thickness measured by the same paediatric cardiologist
  • Age-sex-matched healthy controls
  • Single paediatric cardiologist measurements
  • CIMT and EAT thickness measured by the same paediatric cardiologist

Main finding

As reported in the abstract

  • EAT thickness significantly higher in patients
  • CIMT: no significant differences

Observational data: associations, not effects.

Further findings

Correlation of disease duration and baseline disease activity with EAT thickness

No correlation between disease duration, baseline disease activity, and EAT thickness

BD-related features

Oral aphthous (n)
30
Mucocutaneous findings (n)
22
Uveitis (n)
5
Vascular involvement (n)
4
Neurological involvement (n)
4
Gastrointestinal involvement (n)
2
  • All patients inactive at the time of evaluation

Original publication

Evaluation of epicardial adipose tissue thickness and carotid intima-media thickness in children with Behçet's disease. Clin Exp Rheumatol. Published 6 April 2024. doi:10.55563/clinexprheumatol/ghk2ya

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