A new tool supporting the diagnosis of childhood-onset Behçet’s disease: venous wall thickness
Authors' conclusion
Increased VWT was present not only in BD patients with vascular involvement but also in those without.
Study context
- Population
- Paediatric patients classified with Behçet's disease (BD) according to the 2015 international paediatric BD criteria in a single centre, and healthy age-matched controls35 patients · 27 controls
- Participants
- 13 / 22 / 27
- Exposure
- Childhood-onset definite and incomplete BD vs healthy age-matched controls
- Definite BDn = 13
- Incomplete BDn = 22
- Healthy controlsn = 27reference
- Outcome
- Lower extremity VWT (intima-media thickness by US of common femoral vein (CFV), femoral vein (FV), vena saphena magna, vena saphena parva and PV)
Methodological detailsprospective, age-matched healthy controls
- Prospective
- Age-matched healthy controls
Main finding
As reported in the abstract
Median VWT, all lower extremity veins on both sides
- Median venous wall thickness (VWT) of both definite and incomplete BD significantly higher than controls in all veins on both sides
Observational data: associations, not effects.
Further findings
Diagnostic performance of best VWT cut-off values, all lower extremity veins
- Sensitivity
- between 63% and 86%
- Specificity
- between 71% and 100%
Original publication
A new tool supporting the diagnosis of childhood-onset Behçet’s disease: venous wall thickness. Rheumatology (Oxford). Published 28 May 2022. doi:10.
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