Vasculitis & polymyalgia rheumatica
Epidemiology and clinical characteristics of biopsy-confirmed adult-onset IgA vasculitis in southern Sweden
Authors' conclusion
Adult-onset IgAV is rare in southern Sweden with the incidence higher in men than in women. IgAV frequently affects the kidneys and leads to chronic kidney disease in adults, although the long-term renal outcome appears favourable compared with other small-vessel vasculitides affecting the kidneys.
Study context
- Population
- Adults (≥18 years) with biopsy-confirmed Immunoglobulin A vasculitis (IgAV) (ICD-10 D69.0), Skåne, Sweden, 2000–201919 women
- Participants
- 59 adults
- Outcome
- Annual incidence and point prevalence of biopsy-confirmed IgAV
Methodological detailsbiopsy-confirmed cases, medical record review
- Biopsy-confirmed cases
- Medical record review
Main finding
As reported in the abstract
Annual incidence of biopsy-confirmed adult-onset IgAV
Incidence
3 per 1 000 000
Incidence, men vs women (p=0.004)
4 vs 2/1 000 000
Observational data: associations, not effects.
Further findings
Clinical presentation
- Non-thrombocytopenic purpura
- 97%
- Renal involvement
- 78%
- Arthritis/arthralgia
- 59%
- Gastrointestinal symptoms
- 39%
Renal outcome during follow-up
- Developed CKD stage ≥G3 a
- 15%
- Progressed to end-stage kidney disease
- 1
Original publication
Epidemiology and clinical characteristics of biopsy-confirmed adult-onset IgA vasculitis in southern Sweden. RMD Open. Published 5 February 2024. doi:10.
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