Do the Provisional Paediatric Rheumatology International Trials Organisation Enthesitis/Spondylitis‐Related Juvenile Idiopathic Arthritis Criteria Capture Youth With Axial Spondyloarthritis?
Authors' conclusion
Phenotypic differences of children with axJSpA between those who were and were not classified by the PRINTO criteria were primarily due to peripheral disease manifestations and HLA-B27 positivity.
Study context
- Population
- Youth diagnosed with juvenile spondyloarthritis (SpA) who met the axial juvenile SpA (axJSpA) classification criteria
- Participants
- 158 participants
- Exposure
- Patients meeting vs not meeting the Paediatric Rheumatology International Trials Organisation (PRINTO) provisional ERA criteria
- Met PRINTO criterian = 107
- Outcome
- Fulfilment of PRINTO provisional ERA criteria
Methodological detailsretrospective, central magnetic resonance imaging (MRI) review by at least two raters
- Retrospective
- Central MRI review by at least two raters
Main finding
As reported in the abstract
Met PRINTO criteria
68%
107
- Did not fulfil any of the three major PRINTO criteria due to lack of peripheral disease manifestations
- 41 (26%)
Observational data: associations, not effects.
Original publication
Do the Provisional Paediatric Rheumatology International Trials Organisation Enthesitis/Spondylitis‐Related Juvenile Idiopathic Arthritis Criteria Capture Youth With Axial Spondyloarthritis? Arthritis Care Res (Hoboken). Published 4 February 2025. doi:10. 1002/ acr. 25491
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