Pediatric rheumatology

Do the Provisional Paediatric Rheumatology International Trials Organisation Enthesitis/Spondylitis‐Related Juvenile Idiopathic Arthritis Criteria Capture Youth With Axial Spondyloarthritis?

Arthritis Care Res (Hoboken)Published Cross-sectional study

Authors' conclusion

Phenotypic differences of children with axJSpA between those who were and were not classified by the PRINTO criteria were primarily due to peripheral disease manifestations and HLA-B27 positivity.

Study context

Population
Youth diagnosed with juvenile spondyloarthritis (SpA) who met the axial juvenile SpA (axJSpA) classification criteria
Participants
158 participants
Exposure
Patients meeting vs not meeting the Paediatric Rheumatology International Trials Organisation (PRINTO) provisional ERA criteria
  • Met PRINTO criterian = 107
Outcome
Fulfilment of PRINTO provisional ERA criteria
Methodological detailsretrospective, central magnetic resonance imaging (MRI) review by at least two raters
  • Retrospective
  • Central MRI review by at least two raters

Main finding

As reported in the abstract

Met PRINTO criteria

68%

107

Did not fulfil any of the three major PRINTO criteria due to lack of peripheral disease manifestations
41 (26%)

Observational data: associations, not effects.

Original publication

Do the Provisional Paediatric Rheumatology International Trials Organisation Enthesitis/Spondylitis‐Related Juvenile Idiopathic Arthritis Criteria Capture Youth With Axial Spondyloarthritis? Arthritis Care Res (Hoboken). Published 4 February 2025. doi:10.1002/acr.25491

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