Pediatric rheumatology

Classification of Nonsystemic Juvenile Idiopathic Arthritis Using the Provisional Paediatric Rheumatology International Trials Organisation Criteria

J RheumatolPublished Retrospective cohort study

Authors' conclusion

The provisional PRINTO criteria successfully reclassified a substantial proportion of previously undifferentiated JIA cases, improving diagnostic categorization by addressing some ILAR classification limitations.

Study context

Population
Patients with nonsystemic juvenile idiopathic arthritis (JIA) at a single tertiary pediatric rheumatology center; mean age at enrollment 169.8 (SD 59.2) months
Participants
310 patients
Exposure
Provisional Paediatric Rheumatology International Trials Organisation (PRINTO) criteria vs International League of Associations for Rheumatology (ILAR) criteria for classification of nonsystemic JIA
Outcome
Distribution of JIA categories under ILAR and provisional PRINTO criteria
Methodological detailssingle-centre, tertiary pediatric rheumatology center
  • Single-centre
  • Tertiary pediatric rheumatology center

Main finding

As reported in the abstract

Distribution of JIA categories
ILAR: oligoarticular JIA
136 (43.9%)
ILAR: enthesitis-related arthritis
73 (23.5%)
ILAR: Rheumatoid factor (RF)-negative polyarticular JIA
34 (11%)
ILAR: Psoriatic arthritis (PsA)
12 (3.9%)
ILAR: RF-positive polyarticular JIA
7 (2.3%)
ILAR: undifferentiated JIA
48 (15.5%)
PRINTO: early-onset ANA-positive JIA
107 (34.5%)
PRINTO: other JIA
93 (30%)
PRINTO: enthesitis/spondylitis-related JIA
88 (28.4%)
PRINTO: RF-positive JIA
17 (5.5%)
PRINTO: unclassified JIA
5 (1.6%)

Observational data: associations, not effects.

Further findings

ILAR categories within PRINTO other JIA (n = 93)

Oligoarticular JIA
54.8%
RF-negative polyarticular JIA
21.5%
Undifferentiated JIA
11.8%
Enthesitis-related arthritis
6.5%
PsA
5.4%

Original publication

Classification of Nonsystemic Juvenile Idiopathic Arthritis Using the Provisional Paediatric Rheumatology International Trials Organisation Criteria. J Rheumatol. Published 1 February 2026. doi:10.3899/jrheum.2025-0551

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