Vasculitis & polymyalgia rheumatica
Comparison of long-term survival after endovascular treatment versus medical therapy in patients with Takayasu's arteritis and pulmonary artery stenosis
Authors' conclusion
Under basic medicine, PTPA therapy improves the long-term survival of TAK patients with PAS and PH compared to medical treatment alone.
Study context
- Population
- TAK patients with pulmonary artery stenosis (PAS) and pulmonary hypertension (PH) (women, 101; men, 28; mean age, 40.5 years)median follow-up 54 months
- Participants
- 129 patients
- Exposure
- Percutaneous transluminal pulmonary angioplasty vs medical treatment
- Percutaneous transluminal pulmonary angioplasty (PTPA)n = 54
- Medical treatmentn = 75reference
- Outcome
- Cardiac mortality
Main finding
As reported in the abstract
- PTPA vs Medical treatment: P = 0.031
Observational data: associations, not effects.
Further findings
| Outcome | P value |
|---|---|
| WHO functional classSignificantly improved in the PTPA group | P < 0.001 |
| 6-min walk distance (6MWD)Significantly improved in the PTPA group | P = 0.004 |
Original publication
Comparison of long-term survival after endovascular treatment versus medical therapy in patients with Takayasu's arteritis and pulmonary artery stenosis. Clin Exp Rheumatol. Published 1 September 2022. doi:10.
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