Vasculitis & polymyalgia rheumatica
The performance of duplex ultrasonography for the assessment of renal artery stenosis in Takayasu’s arteritis patients
Authors' conclusion
In the present study, it has been demonstrated that RPSV and RIR possess substantial diagnostic value as ultrasonic parameters for diagnosing RAS in TAK patients.
Study context
- Population
- TAK patients admitted to Peking Union Medical College Hospital, 2017–2022, with renal artery US and angiography within 4 weeks314 renal arteries
- Participants
- 115 patients
- Comparison
- Duplex ultrasonography parameters vs angiography for renal artery stenosis (RAS) in TAK
- Outcome
- Diagnostic efficacy of duplex US for renal artery involvement and degrees of RAS (optimal thresholds by ROC)
Methodological detailsretrospective, single-centre, angiography as reference
- Retrospective
- Single-centre
- Angiography as reference
Performance
As reported in the abstract
Diagnosis of RAI, ≥ 50% RAS and ≥ 70% RAS
| Test or model | Threshold for renal artery involvement (RAI) | Threshold for ≥ 50% RAS | Threshold for ≥ 70% RAS | Sensitivity, specificity, accuracy | AUC for ≥ 50% RAS | AUC for ≥ 70% RAS | Threshold for ≥ 70% RAS (aortic PSV < 140 cm/s) | Sensitivity | Specificity | Accuracy |
|---|---|---|---|---|---|---|---|---|---|---|
| RPSV | 143 cm/s | 152 cm/s | 183 cm/s | greater than 80% | 0.908 | 0.876 | ||||
| RIR | 4.6 | 5.6 | 6.4 | 0.910 | 0.882 | |||||
| RAR | 2.2 | 84.00% | 89.93% | 89.08% |
Threshold for renal artery involvement (RAI)
RPSV143 cm/s
RIR4.6
RAR— not stated in the abstract
Threshold for ≥ 50% RAS
RPSV152 cm/s
RIR5.6
RAR— not stated in the abstract
Threshold for ≥ 70% RAS
RPSV183 cm/s
RIR6.4
RAR— not stated in the abstract
Sensitivity, specificity, accuracy
RPSVgreater than 80%
RIR— not stated in the abstract
RAR— not stated in the abstract
AUC for ≥ 50% RAS
RPSV0.908
RIR0.910
RAR— not stated in the abstract
AUC for ≥ 70% RAS
RPSV0.876
RIR0.882
RAR— not stated in the abstract
Threshold for ≥ 70% RAS (aortic PSV < 140 cm/s)
RPSV— not stated in the abstract
RIR— not stated in the abstract
RAR2.2
Sensitivity
RPSV— not stated in the abstract
RIR— not stated in the abstract
RAR84.00%
Specificity
RPSV— not stated in the abstract
RIR— not stated in the abstract
RAR89.93%
Accuracy
RPSV— not stated in the abstract
RIR— not stated in the abstract
RAR89.08%
Further findings
US parameters across 4 stenosis groups (noninvolvement, < 50%, 50-69%, 70-99%)
- Significant differences in RAR and RIR among the four groups
- all P < 0.05
- No significant differences in RPSV and AT between 50-69% and 70-99% stenosis
- Discrimination of interlobar PSV (IPSV) and interlobar RI (IRI) not significant; IEDV not significant among the four groups
Original publication
The performance of duplex ultrasonography for the assessment of renal artery stenosis in Takayasu’s arteritis patients. Arthritis Res Ther. Published 3 August 2023. doi:10.
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