Vasculitis & polymyalgia rheumatica
Carotid artery ultrasonography and shear wave elastography in Takayasu's arteritis: a comparative analysis with diabetes mellitus
Authors' conclusion
Our study revealed distinctive vascular alterations and atherosclerotic changes when compared to advanced atherosclerosis associated with T2DM.
Study context
- Population
- Patients with TAK and patients with T2DM studied with carotid artery B mode US and shear wave elastography (SWE)
- Participants
- 72 vs 74
- Exposure
- TAK vs T2DM
- TAKn = 72
- T2DMn = 74reference
- Outcome
- CCA IMT, outer diameter and arterial stiffness (SWE values); atherosclerotic plaques
Methodological detailscomparative analysis
- Comparative analysis
Main finding
As reported in the abstract
CCA IMT, outer diameter and stiffness
- Mean common carotid artery (CCA) intima-media thickness (IMT), outer diameter and stiffness significantly elevated in TAK vs T2DM
- Carotid artery plaques evenly distributed between groups, but anatomical localisation and composition differed significantly
Observational data: associations, not effects.
Further findings
Atherosclerotic risk and systolic blood pressure (BP)
- TAK had significantly lower atherosclerotic risk but higher systolic BP vs T2DM
Previous cardiovascular (CV) diseases
- Coronary artery disease (CAD) more prevalent in T2DM; cerebrovascular diseases more frequent in TAK
Original publication
Carotid artery ultrasonography and shear wave elastography in Takayasu's arteritis: a comparative analysis with diabetes mellitus. Clin Exp Rheumatol. Published 25 April 2024. doi:10. 55563/ clinexprheumatol/ gyo8xt
Composed by AI from the published abstract and checked against it. How Briefs are made →