Vasculitis & polymyalgia rheumatica

Carotid artery ultrasonography and shear wave elastography in Takayasu's arteritis: a comparative analysis with diabetes mellitus

Clin Exp RheumatolPublished Cross-sectional study

Authors' conclusion

Our study revealed distinctive vascular alterations and atherosclerotic changes when compared to advanced atherosclerosis associated with T2DM.

Study context

Population
Patients with TAK and patients with T2DM studied with carotid artery B mode US and shear wave elastography (SWE)
Participants
72 vs 74
Exposure
TAK vs T2DM
  • TAKn = 72
  • T2DMn = 74reference
Outcome
CCA IMT, outer diameter and arterial stiffness (SWE values); atherosclerotic plaques
Methodological detailscomparative analysis
  • Comparative analysis

Main finding

As reported in the abstract

CCA IMT, outer diameter and stiffness
  • Mean common carotid artery (CCA) intima-media thickness (IMT), outer diameter and stiffness significantly elevated in TAK vs T2DM
  • Carotid artery plaques evenly distributed between groups, but anatomical localisation and composition differed significantly

Observational data: associations, not effects.

Further findings

Atherosclerotic risk and systolic blood pressure (BP)

TAK had significantly lower atherosclerotic risk but higher systolic BP vs T2DM

Previous cardiovascular (CV) diseases

Coronary artery disease (CAD) more prevalent in T2DM; cerebrovascular diseases more frequent in TAK

Original publication

Carotid artery ultrasonography and shear wave elastography in Takayasu's arteritis: a comparative analysis with diabetes mellitus. Clin Exp Rheumatol. Published 25 April 2024. doi:10.55563/clinexprheumatol/gyo8xt

Composed by AI from the published abstract and checked against it. How Briefs are made →

Get them every week

New studies on this topic in My Week and in your Monday e-mail.

We e-mail you a sign-in link and a code. No password, no spam.