Spondyloarthritis & psoriatic arthritis

Clinical enthesitis in patient with psoriatic arthritis, a systematic literature review with metaanalysis

Joint Bone SpinePublished Systematic review and meta-analysis

Authors' conclusion

Enthesitis is a frequent manifestation in PsA, concerning close to half the patients, and is more prevalent in trials than in observational studies, reflecting recruitment patterns.

Study context

Population
Adult psoriatic arthritis (PsA) patients in studies reporting information related to enthesitis
Participants
84,262 patients212 studies
Comparison
Trials vs Observational studies
Outcome
Prevalence of clinical enthesitis (number of patients with at least one enthesitis)
Methodological detailsunivariate random-effects meta-analysis, PubMed 2010-2023
  • Univariate random-effects meta-analysis
  • PubMed 2010-2023

Pooled result

As reported in the abstract

Pooled prevalence of clinical enthesitis
Pooled prevalence, overall population
41.6% (95% CI 37.4-45.8)

Further pooled results

Enthesitis scores used

Leeds Enthesitis Index (LEI), the most widely-used score
63.7%
Number of enthesitis varied by score, lowest with LEI

Impact of enthesitis

Patients with enthesitis had higher disease activity and disease burden than those without

Original publication

Clinical enthesitis in patient with psoriatic arthritis, a systematic literature review with metaanalysis. Joint Bone Spine. Published 30 October 2024. doi:10.1016/j.jbspin.2024.105807

Composed by AI from the published abstract and checked against it. How Briefs are made →

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