Spondyloarthritis & psoriatic arthritis
Sleep Problems in Patients With Psoriatic Arthritis: A Systematic Literature Review and Metaanalysis
Authors' conclusion
Poor sleep quality is prevalent in patients with PsA.
Study context
- Population
- Patients with psoriatic arthritis (PsA)36 studies
- Comparison
- PsA vs healthy controls vs psoriasis
- Outcome
- Sleep problems in PsA
Methodological detailsPubMed and Embase, 26 cross-sectional, 7 cohort, and 3 interventional studies
- PubMed and Embase
- 26 cross-sectional, 7 cohort, and 3 interventional studies
Pooled result
As reported in the abstract
Prevalence of poor sleep quality (Pittsburgh Sleep Quality Index; meta-analysis of 6 studies)
Prevalence of poor sleep quality (Pittsburgh Sleep Quality Index; meta-analysis of 6 studies) PsA 72.9% (95% CI 63–81.8) · Healthy controls 26.9% (95% CI 11.7–45.4) · Psoriasis 59.8% (95% CI 46.9–72.1)
I2
Further pooled results
Prevalence of self-reported sleep problems in PsA
- Range
- 30% to 85%
Other findings
- Sleep disturbance ranked in top 4 HRQoL domains affected by PsA
- One study suggested a bidirectional relationship between PsA and obstructive sleep apnea
- Predictors: anxiety, pain, ESR, depression, fatigue, physical function, tender or swollen joint count
- TNFi, guselkumab and filgotinib (JAKi) associated with improved sleep outcomes
Original publication
Sleep Problems in Patients With Psoriatic Arthritis: A Systematic Literature Review and Metaanalysis. J Rheumatol. Published 1 May 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →