Spondyloarthritis & psoriatic arthritis
Characterisation of prodromal and very early psoriatic arthritis: a systematic literature review informing a EULAR taskforce
Authors' conclusion
Joint pain, arthralgia and entheseal involvement detected by imaging were frequent in individuals with PsO at risk for imminent PsA. Very early PsA was mainly oligoarticular.
Study context
- Population
- Patients transitioning from psoriasis (PsO) to psoriatic arthritis (PsA) and from undifferentiated arthritis (UA) to PsA18 PsO/PsA + 3 UA/PsA studies
- Outcome
- Clinical and imaging characteristics before PsA onset and at time of PsA diagnosis
Methodological detailsinforming a EULAR taskforce, no meta-analysis (excessive data heterogeneity)
- Informing a EULAR taskforce
- No meta-analysis (excessive data heterogeneity)
Pooled result
As reported in the abstract
Characteristics of PsO-to-PsA transition
- Patients with PsO who developed PsA often reported joint pain, joint tenderness and functional limitations
- Arthralgia associated with subsequent PsA development (PsO, n=669; incident PsA, n=99)
- Subclinical enthesopathy on imaging appeared linked to later PsA development (PsO=325; incident PsA=39)
- 14 cohort studies, 2 case-control studies
Further pooled results
Clinical presentation at PsA onset (incident PsA, N=214)
- Peripheral arthritis, mainly oligo-arthritis, most frequent pattern; mean number of swollen joints ranged
- 1.5 to 3.2
Original publication
Characterisation of prodromal and very early psoriatic arthritis: a systematic literature review informing a EULAR taskforce. RMD Open. Published 22 June 2023. doi:10.
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