Spondyloarthritis & psoriatic arthritis

Management of Enthesitis in Patients With Psoriatic Arthritis: An Updated Literature Review Informing the 2021 Group for Research and Assessment in Psoriasis and Psoriatic Arthritis (GRAPPA) Treatment Recommendations

J RheumatolPublished Systematic review of randomised trials

Authors' conclusion

Several classes of systemic conventional and advanced therapies and local measures were recommended for active enthesitis in patients with PsA.

Study context

Population
Children and adults with psoriatic arthritis (PsA) and enthesitis41 RCTs
Comparison
Pharmaceutical and nonpharmaceutical interventions for enthesitis in PsA
Outcome
Enthesitis treatment response (change in total enthesitis score or proportion with complete resolution)
Methodological detailssystematic literature review, quality of evidence graded, For each intervention, the response effect size was summarized and the quality of evidence was graded; recommendations were then formulated for pharmacological and nonpharmacological therapies
  • Systematic literature review
  • Quality of evidence graded
  • For each intervention, the response effect size was summarized and the quality of evidence was graded; recommendations were then formulated for pharmacological and nonpharmacological therapies

Pooled result

As reported in the abstract

Enthesitis treatment response
  • 41 RCTs included; each intervention graded

Original publication

Management of Enthesitis in Patients With Psoriatic Arthritis: An Updated Literature Review Informing the 2021 GRAPPA Treatment Recommendations. J Rheumatol. Published 1 November 2022. doi:10.3899/jrheum.220312

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