Lupus & antiphospholipid syndrome

Clinical disease activity index applicability in lupus arthropathy: Unraveling underdiagnosed joint activity

LupusPublished Cross-sectional study

Authors' conclusion

The CDAI was not directly associated with the presence of arthritis by the joint criteria of SLEDAI-2K and the presence of JA was significantly associated with the CDAI but not with arthritis at SLEDAI-2K.

Study context

Population
Patients with SLE
Participants
127 patients
Exposure
Clinical Disease Activity Index (CDAI) vs SLEDAI-2K articular domain for detecting joint activity in SLE
  • CDAIn = 32
  • SLEDAI-2Kn = 17reference
Outcome
Association between CDAI and arthritis by SLEDAI-2K, and with presence of Jaccoud-type arthropathy

Main finding

As reported in the abstract

Joint activity detected
Patients with CDAI activity not scoring in SLEDAI-2K articular domain
16 (50%)

Observational data: associations, not effects.

Further findings

Association of Jaccoud-type arthropathy with arthritis activity

JA associated with CDAI arthritis activity
P = 0.014
JA not associated with SLEDAI-2K joint criteria
P = 0.524

Original publication

Clinical disease activity index applicability in lupus arthropathy: Unraveling underdiagnosed joint activity. Lupus. Published 16 October 2023. doi:10.1177/09612033231206454

Composed by AI from the published abstract and checked against it. How Briefs are made →

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