Osteoarthritis

Causal Factors for Osteoarthritis: A Scoping Review of Mendelian Randomization Studies

Arthritis Care Res (Hoboken)Published Scoping review of Mendelian randomization studies

Study context

Population
Mendelian randomization (MR) studies of osteoarthritis (OA) evaluating the causal role of modifiable risk factors141 exposure-association analyses
Participants
45 studies
Outcome
Causal associations between modifiable exposures and OA
Methodological detailsPRISMA Extension for Scoping Reviews, literature search before December 2021
  • PRISMA Extension for Scoping Reviews
  • Literature search before December 2021

Main finding

As reported in the abstract

Analyses reporting causal associations (P < 0.05)

60

Unique publications with causal associations

36

Analyses with MR-Egger sensitivity analyses

45

Original publication

Causal Factors for Osteoarthritis: A Scoping Review of Mendelian Randomization Studies. Arthritis Care Res (Hoboken). Published 7 February 2024. doi:10.1002/acr.25252

Composed by AI from the published abstract and checked against it. How Briefs are made →

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