Osteoarthritis

Burden of Knee Osteoarthritis in 204 Countries and Territories, 1990–2019: Results From the Global Burden of Disease Study 2019

Arthritis Care Res (Hoboken)Published Descriptive epidemiological study

Authors' conclusion

The prevalence, incidence, YLDs, and age-standardized rates of knee OA increased substantially in most countries and regions from 1990 to 2019.

Study context

Population
Knee osteoarthritis (OA) in 204 countries and territories, 1990–2019, by age, sex and SDI
Outcome
Prevalence, incidence, years lived with disability (YLDs) and age-standardized rates of knee OA, and burden attributable to high BMI
Follow-up
2019
Methodological detailsGlobal Burden of Disease Study 2019 analysis, Bayesian meta-regression (DisMod-MR 2.1), 204 countries and territories, 1990–2019
  • Global Burden of Disease Study 2019 analysis
  • Bayesian meta-regression (DisMod-MR 2.1)
  • 204 countries and territories
  • 1990–2019

Main finding

As reported in the abstract

Global knee OA burden
Global prevalence (million), 95% UI 315.3 to 417.4
≈364.6
Age-standardized prevalence per 100,000, 95% UI 3,793.0 to 5,004.9
4,376.0
Increase in age-standardized prevalence 1990–2019
7.5%
Incident cases (million), 95% UI 25.6 to 33.7
≈29.5
Age-standardized incidence per 100,000, 95% UI 303.4 to 398.9
350.3
Age-standardized YLD per 100,000, 95% UI 68.5 to 281.3
138.2
Increase in age-standardized YLD from 1990, 95% UI 7.1 to 8.4
7.8%
YLD attributable to high BMI, 95% UI 12.1 to 34.2
22.4%
Increase in high-BMI-attributable YLD since 1990
40.5%

Original publication

Burden of Knee Osteoarthritis in 204 Countries and Territories, 1990–2019: Results From the Global Burden of Disease Study 2019. Arthritis Care Res (Hoboken). Published 13 July 2023. doi:10.1002/acr.25158

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