Global Burden of Osteoarthritis Attributable to High Body Mass Index, 1990 to 2021: Insights From the Global Burden of Disease Study 2021
Authors' conclusion
Between 1990 and 2021, the global burden of OA attributable to high BMI increased markedly, with a consistent upward trend across most regions. The burden was more pronounced among women, middle-aged and older adults, and populations in high-SDI regions, reflecting a growing and uneven global health challenge.
Study context
- Population
- Osteoarthritis (OA) burden attributable to high body mass index (BMI) across 204 countries and regions, 1990–2021204 countries and regions
- Primary endpoint
- YLDs and age-standardized YLD rates of OA attributable to high BMI
- Follow-up
- 1990 to 2021
Methodological detailsjoinpoint regression, 204 countries and regions
- Joinpoint regression
- 204 countries and regions
Primary result
As reported in the abstract
Years lived with disability (YLDs), 1990 to 2021 (increased threefold)
1,449,681 to 4,422,954
Age-standardized YLD rate per 100,000, 1990
33.97
95% UI −3.14 to 102.31
Age-standardized YLD rate per 100,000, 2021
50.59
95% UI −4.81 to 141.35
Average annual percentage change
1.11
95% CI 1.07–1.14
Further findings
OA YLDs attributable to high BMI by sex
- Higher in women than men across all age groups
Age-standardized OA YLD rates by Sociodemographic Index (SDI)
- Positively correlated with SDI levels; higher burdens in higher-SDI regions
Original publication
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