Real‐World Cost‐Effectiveness of a Standardized Education and Exercise Therapy Program for Hip and Knee Osteoarthritis Compared to Usual Care
Main finding · Adjusted INMB, MOH perspectiveResult — go to the resultAdjusted INMB 6,065 $ 95% CI $3,648-$8,482Authors' conclusion
GLA:D had a positive INMB compared to UC from the MOH perspective over 12 months. The INMB remained positive but was less certain over a lifetime or when out-of-pocket and private insurance costs were considered.
Study context
- Population
- People aged >45 years diagnosed with hip and/or knee OA, Alberta, Canada72% female
- Participants
- 254 people
- Exposure
- GLA:D standardized education and exercise therapy program vs usual care
- GLA:Dn = 127
- Usual care (UC)n = 127reference
- Outcome
- Adjusted INMB (Canadian dollars), $30,000/QALY willingness-to-pay threshold, Ministry of Health (MOH) perspective
- Follow-up
- 12 months
Methodological detailscost-effectiveness analysis, Markov model (lifetime horizon, 3% discounting), probabilistic sensitivity analyses
- Cost-effectiveness analysis
- Markov model (lifetime horizon, 3% discounting)
- Probabilistic sensitivity analyses
Main finding
Adjusted INMB, MOH perspective
Adjusted incremental net monetary benefit (INMB)
6,065 $
95% CI $3,648-$8,482
As reported in the abstract
Observational data: associations, not effects.
Further findings
| Outcome | Estimate |
|---|---|
| Adjusted INMB, health care perspective (MOH, private insurance, out-of-pocket) · 12 months | adjusted INMB 499 $ (95% CI -$2,913 to $3,912) |
| INMB over lifetime, MOH perspective54% probability of being cost-effective at $30,000 per QALY | INMB 6,574 $ |
| INMB over lifetime, health care perspective51% probability of being cost-effective at $30,000 per QALY | INMB 1,775 $ |
Original publication
Real‐World Cost‐Effectiveness of a Standardized Education and Exercise Therapy Program for Hip and Knee Osteoarthritis Compared to Usual Care. Arthritis Care Res (Hoboken). Published 12 July 2025. doi:10.
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