Association of Change in Body Mass Index With Incidence and Progression of the Structural Defects of Hip Osteoarthritis: Data From the Osteoarthritis Initiative and the Cohort Hip and Cohort Knee study
Authors' conclusion
Weight loss may not be an effective strategy for preventing, slowing, or delaying the structural defects of hip osteoarthritis over 4-5 years.
Study context
- Population
- Hips from the Osteoarthritis Initiative (OAI) and the Cohort Hip and Cohort Knee (CHECK) studyhips analysed, not persons
- Exposure
- Change in body mass index (BMI) from baseline to 4-5 years' follow-up
- Outcome
- Incidence (grade ≥2 at follow-up in hips with grade <2 at baseline) and progression (grade increase of ≥1 in hips with grade ≥2 at baseline) of radiographic structural defects of hip OA (modified Croft grade in OAI; Kellgren/Lawrence grade in CHECK)
- Follow-up
- 4-5 years
Methodological details2 independent cohorts (OAI and CHECK), incidence and progression cohorts
- 2 independent cohorts (OAI and CHECK)
- Incidence and progression cohorts
Main finding
As reported in the abstract
Incidence and progression of definite structural defects of hip OA
OAI incidence cohort, hips
5,896
CHECK incidence cohort, hips
1,377
OAI progression cohort, hips
303
CHECK progression cohort, hips
129
Observational data: associations, not effects.
Original publication
Association of Change in Body Mass Index With Incidence and Progression of the Structural Defects of Hip Osteoarthritis: Data From the Osteoarthritis Initiative and the Cohort Hip and Cohort Knee study. Arthritis Care Res (Hoboken). Published 14 February 2023. doi:10.
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