Sjögren's disease & overlap diseases

Analysis of risk factors and development of a nomogram prediction model for renal tubular acidosis in primary Sjogren syndrome patients

Arthritis Res TherPublished Retrospective cohort study

Authors' conclusion

We developed a nomogram to predict RTA occurrence in pSS patients

Study context

Population
Inpatients with pSS, January 2012 to January 2024
Participants
99 inpatients
Outcome
Risk factors for renal tubular acidosis (RTA) in pSS and nomogram prediction of pSS-RTA
Methodological detailssingle-centre, bootstrap resampling, multivariate logistic regression, nomogram prediction model
  • Single-centre
  • Bootstrap resampling
  • Multivariate logistic regression
  • Nomogram prediction model

Main finding

As reported in the abstract

Hosmer-Lemeshow test p-value (good fit)

0.657

AUC, training group

0.912

AUC, validation group

0.896

Observational data: associations, not effects.

Further findings

No association between pSS-RTA severity and risk factors

Original publication

Analysis of risk factors and development of a nomogram prediction model for renal tubular acidosis in primary Sjogren syndrome patients. Arthritis Res Ther. Published 22 August 2024. doi:10.1186/s13075-024-03383-w

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