Sjögren's disease & overlap diseases
Added value of the salivary gland ultrasonography OMERACT score in the ACR/EULAR classification criteria for Sjögren's disease
Authors' conclusion
The accuracy of the ACR/EULAR classification criteria for predicting the clinical diagnosis of SjD remained excellent after incorporating the SGUS OMERACT score and extends the diagnostic options in patients suspected with SjD.
Study context
- Population
- Patients visiting the Sjögren Expertise centre, University Medical Center Groningen, for a diagnostic trajectory because of suspicion of Sjögren's disease (SjD)
- Participants
- 419 consecutive patients
- Comparison
- Salivary gland ultrasonography (SGUS) OMERACT score alone and added to the 2016 ACR/EULAR classification criteria, vs total SGUS Hocevar score, for predicting clinical diagnosis of SjD
- Outcome
- Accuracy (ROC analysis) to predict clinical diagnosis of SjD
Methodological detailsconsecutive patients, single-centre
- Consecutive patients
- Single-centre
Performance
As reported in the abstract
Accuracy to predict clinical diagnosis of SjD
| Test or model | AUC | Sensitivity | Specificity |
|---|---|---|---|
| Highest SGUS OMERACT score | 0.849 | — not stated in the abstract | — not stated in the abstract |
| Total SGUS OMERACT score | 0.868 | — not stated in the abstract | — not stated in the abstract |
| Total Hocevar score | 0.864 | — not stated in the abstract | — not stated in the abstract |
| ACR/EULAR criteria + highest SGUS OMERACT score | 0.974 | 96.4% | 86.5% |
AUC
Highest SGUS OMERACT score0.849
Total SGUS OMERACT score0.868
Total Hocevar score0.864
ACR/EULAR criteria + highest SGUS OMERACT score0.974
Sensitivity
Highest SGUS OMERACT score— not stated in the abstract
Total SGUS OMERACT score— not stated in the abstract
Total Hocevar score— not stated in the abstract
ACR/EULAR criteria + highest SGUS OMERACT score96.4%
Specificity
Highest SGUS OMERACT score— not stated in the abstract
Total SGUS OMERACT score— not stated in the abstract
Total Hocevar score— not stated in the abstract
ACR/EULAR criteria + highest SGUS OMERACT score86.5%
— not stated in the abstract
Original publication
Added value of the salivary gland ultrasonography OMERACT score in the ACR/EULAR classification criteria for Sjögren's disease. Semin Arthritis Rheum. Published 21 May 2024. doi:10.
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