Within-person change in patient-reported outcomes and their association with the wish to undergo joint surgery during a digital first-line intervention for osteoarthritis
Authors' conclusion
Within-person improvements in PROMs are associated with reduced wish for surgery while worsenings with an increased wish for surgery.
Study context
- Population
- Participants in a digital first-line intervention (exercise and education) for knee/hip osteoarthritis (OA), enrolled June 1, 2018 to October 30, 2021, with 3-month follow-up data
- Participants
- 13,961 participants
- Outcome
- Association between within-person change in PROMs and change in wish to undergo joint surgery
- Follow-up
- Last available time point (3, 6, 9, or 12 months)
Methodological detailsasymmetric fixed effect (conditional) logistic regressions
- Asymmetric fixed effect (conditional) logistic regressions
Main finding
As reported in the abstract
Association of PROM changes with wish for surgery
- Improvements in patient-reported outcomes (PROMs) generally associated with reduced likelihood of wishing for surgery; worsening associated with increased likelihood
- For pain, activity impairment, EQ-5D and KOOS/HOOS quality of life (QoL), worsening led to a larger absolute change in probability of wish for surgery than an improvement in the same PROM
Observational data: associations, not effects.
Further findings
Proportion wishing to undergo surgery, baseline to 3 months
- Baseline
- 15.7%
- 3 months
- 13.3%
- Decline
- 2% (95% CI 1.9, 3.0)
Original publication
Within-person change in patient-reported outcomes and their association with the wish to undergo joint surgery during a digital first-line intervention for osteoarthritis. Osteoarthritis Cartilage. Published 1 June 2023. doi:10. 1016/ j. joca. 2023. 05. 011
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