Lifetime Cost-Effectiveness of Structured Education and Exercise Therapy for Knee Osteoarthritis in Australia
Main finding · INMB at population levelResult — go to the resultINMB -A$4090Authors' conclusion
In this economic evaluation of structured education and exercise therapy compared with usual care, the intervention was not cost-effective over the lifetime for all patients but was for the first 9 years and for those with minimal pain.
Study context
- Population
- Hypothetical cohort of adults aged 45 to 84 years with knee OA who would undergo total knee replacement (TKR), Australian health care systemhypothetical cohort
- Participants
- 61,394 participants
- Exposure
- National structured education and exercise therapy program vs usual care
- Outcome
- INMB, with an incremental cost-effectiveness ratio threshold of A$28 033 per QALY gained, health care perspective
- Follow-up
- Lifetime
Methodological detailslife table model combined with Markov model, hypothetical cohort, health care perspective, lifetime horizon, subgroup, deterministic and probabilistic sensitivity analyses
- Life table model combined with Markov model
- Hypothetical cohort
- Health care perspective
- Lifetime horizon
- Subgroup, deterministic and probabilistic sensitivity analyses
Main finding
INMB at population level
Incremental net monetary benefit (INMB)
-A$4090
As reported in the abstract
- Lifetime cost savings
- A$498 307 942 (US $339 922 227)
- Cost savings per individual
- A$7970 (US $5537)
- Fewer quality-adjusted life-year (QALYs) per individual vs usual care
- 0.43
Observational data: associations, not effects.
Further findings
INMB over lifetime, subgroup with no or mild pain at baseline
- Intervention cost-effective over a lifetime only in individuals with no or mild pain at baseline (INMB)
- A$11 [US $8]
Cost-effectiveness by time horizon (subgroup analysis) · first 9 years
- Intervention cost-effective only for the first 9 years
Original publication
Lifetime Cost-Effectiveness of Structured Education and Exercise Therapy for Knee Osteoarthritis in Australia. JAMA Netw Open. Published 1 October 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →