Osteoarthritis

Association between metabolic conditions, physical activity and self-efficacy before and after a first-line exercise and education intervention for osteoarthritis: a longitudinal register study using the SOAD cohort

RMD OpenPublished Register-based cohort study

Authors' conclusion

Metabolic conditions were associated with lower PA and self-efficacy, with differences increasing with the number of co-existing conditions. The baseline disparities associated with metabolic conditions persisted after the intervention, with both groups showing improvement at 3 months but reverting to baseline by 12 months.

Study context

Population
Individuals with knee or hip osteoarthritis (OA) in the Swedish Osteoarthritis and Diabetes cohort undergoing a 6-week exercise and education intervention
Participants
80,893 individuals
Exposure
Metabolic conditions (diabetes, hypertension, overweight/obesity) vs none, before and after a 6-week exercise and education intervention
Outcome
Self-reported PA (weekly minutes) and self-efficacy (ASES, score 10-100) for pain and other symptoms
Follow-up
Baseline, 3 months, 12 months
Methodological detailslongitudinal, linear mixed-effect models adjusted for confounders
  • Longitudinal
  • Linear mixed-effect models adjusted for confounders

Main finding

As reported in the abstract

Differences when all three conditions coexisted (lower PA and self-efficacy with metabolic conditions)
Physical activity (PA) difference, baseline (min)
107 [95% CI: 97; 118]
PA difference, 3 months
97 [86; 108]
PA difference, 12 months
109 [95; 123]
Arthritis Self-Efficacy Scale (ASES)-pain difference, baseline
5.6 [3.9; 7.3]
ASES-pain difference, 3 months
5.9 [4.1; 7.7]
ASES-pain difference, 12 months
8.2 [6.1; 10.4]
ASES-other symptoms difference, baseline
6.1 [4.6; 7.7]
ASES-other symptoms difference, 3 months
6.4 [4.8; 8.0]
ASES-other symptoms difference, 12 months
8.2 [6.3; 10.1]

Observational data: associations, not effects.

Original publication

Association between metabolic conditions, physical activity and self-efficacy before and after a first-line exercise and education intervention for osteoarthritis: a longitudinal register study using the SOAD cohort. RMD Open. Published 29 September 2025. doi:10.1136/rmdopen-2025-005804

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