Vasculitis & polymyalgia rheumatica
Vasculitic neuropathy-related disability, pain, quality of life, and autonomic symptoms: a survey of 312 patients
Authors' conclusion
Neuropathy is common and associated with significant disability, pain and impaired HR-QOL in patients with systemic vasculitis.
Study context
- Population
- Patients with vasculitis (with or without neuropathy) invited by Vasculitis UK71% female
- Participants
- 312 patients
- Exposure
- Probable vasculitic neuropathy vs no neuropathy
- Neuropathyn = 242
- Without neuropathyn = 70reference
- Outcome
- Disability, pain and HR-QOL by neuropathy status
Methodological detailsanonymous online survey, self-reported
- Anonymous online survey
- Self-reported
Main finding
As reported in the abstract
Probable vasculitic neuropathy prevalence
78%
Formally diagnosed with neuropathy
52%
Observational data: associations, not effects.
Further findings
| Outcome | Neuropathy | Without neuropathyMedian | P value |
|---|---|---|---|
| Disability, I-RODS centile (lower = more disability) | mean 63.1 (SD 17.3) | — withheld: not confirmed against the abstract | P < 0.0001 |
| Disability, INCAT scale | median 2 (IQR 1–4) | 0.5 (IQR 0–2) | P < 0.0001 |
| Disability, modified Rankin scale | median 2 (IQR 1–3) | 2 (IQR 1–2) | P = 0.0002 |
| Pain, 11-point rating scale | mean 4.6 (SD 2.6) | — withheld: not confirmed against the abstract | P = 0.0009 |
— withheld: the automatic checks could not confirm the value against the abstract
- Health-related quality of life (HR-QOL), EQ5D-3L summary index
- P < 0.0001
Formally diagnosed with neuropathy
- Formally diagnosed with neuropathy
- 52%
Autonomic symptoms
- Reported by two-thirds; not associated with neuropathy
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Vasculitic neuropathy-related disability, pain, quality of life, and autonomic symptoms: a survey of 312 patients. Rheumatology (Oxford). Published 30 January 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →