Vasculitis & polymyalgia rheumatica
Vasculitic peripheral neuropathy in patients with provisional cutaneous arteritis
Authors' conclusion
VPN was prevalent in patients with provisional CA. Clinical features alone were insufficient to predict nerve involvement.
Study context
- Population
- Patients with provisional cutaneous arteritis (CA) (skin-limited medium-vessel vasculitis with neuropathic symptoms in the lower limbs irrespective of nerve biopsy), Severance Hospital, 2011–2024; median age 51.0 years, 36.1% male
- Participants
- 36 patients
- Exposure
- Provisional CA with vasculitic peripheral neuropathy (VPN) vs without VPN
- VPNn = 22
- Outcome
- Prevalence and electrophysiological features of VPN
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Electrophysiological evidence of VPN (prevalence)
VPN
61.1%
22
Observational data: associations, not effects.
Further findings
Type of neuropathy among patients with VPN
- Pure sensory neuropathy
- 59.1%
- Sensorimotor involvement
- 40.9%
Most frequently affected nerves
- Peroneal
- 63.6%
- Sural
- 54.5%
Age, sex, skin manifestations, laboratory findings: VPN vs without VPN
- No significant differences between patients with and without VPN
Original publication
Vasculitic peripheral neuropathy in patients with provisional cutaneous arteritis. Clin Exp Rheumatol. Published 23 October 2025. doi:10.
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