Vasculitis & polymyalgia rheumatica
Performance in adults of the EULAR/PRINTO/PRES (Ankara 2008) classification criteria for IgA vasculitis
Authors' conclusion
The revised EULAR/PReS-endorsed Ankara 2008 IgAV classification criteria perform well in adults with IgAV and are appropriate for use in clinical research.
Study context
- Population
- Adults with IgA vasculitis (IgAV) and comparators with other forms of small-vessel and medium-vessel vasculitis in an international observational cohort; validation in a multicentre Turkish vasculitis registry178 IgAV cases and 1705 comparators
- Comparison
- Revised EULAR/Pediatric Rheumatology European Society (PReS)-endorsed Ankara 2008 IgAV classification criteria vs other small- and medium-vessel vasculitis comparators
- Outcome
- Sensitivity and specificity of the classification criteria for IgAV in adults
Methodological detailsinternational observational cohort, independent validation cohort, multicentre
- International observational cohort
- Independent validation cohort
- Multicentre
Performance
As reported in the abstract
Classification performance of the revised criteria for IgAV in adults
| Test or model | Sensitivity | Specificity | Sensitivity, validation set | Specificity, validation set |
|---|---|---|---|---|
| Revised criteria | 76.4% (95% CI 69.8% to 82.2%) | 94.5% (95.0% CI 93.4% to 95.1%) | 97.8% (95% CI 94.0% to 99.0%) | 85.0% (95.0% CI 78.0% to 90.0%) |
Revised criteria
Sensitivity76.4% (95% CI 69.8% to 82.2%)
Specificity94.5% (95.0% CI 93.4% to 95.1%)
Sensitivity, validation set97.8% (95% CI 94.0% to 99.0%)
Specificity, validation set85.0% (95.0% CI 78.0% to 90.0%)
Original publication
Performance in adults of the EULAR/PRINTO/PRES (Ankara 2008) classification criteria for IgA vasculitis. RMD Open. Published 21 July 2025. doi:10.
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