Spondyloarthritis & psoriatic arthritis
Value of the central sensitisation inventory in patients with axial spondyloarthritis
Authors' conclusion
In this large cross-sectional study in patients with axSpA, the CSI appears as a useful initial CS assessment questionnaire.
Study context
- Population
- Consecutive outpatients with axial spondyloarthritis (axSpA) from the Groningen Leeuwarden AxSpA cohort; 63% male, 64% r-axSpA, median symptom duration 12 years (IQR 5–24), mean ASDAS 2.1±1.0
- Participants
- 201 outpatients
- Exposure
- Central Sensitisation Inventory (CSI)≥40 vs CSI<40
- Outcome
- Quantitative sensory testing (QST) (PPT, TS, CPM) stratified by CSI≥40
Methodological detailsconsecutive outpatients, Groningen Leeuwarden AxSpA cohort
- Consecutive outpatients
- Groningen Leeuwarden AxSpA cohort
Main finding
As reported in the abstract
- CSI≥40: significantly lower pressure pain threshold (PPTs) and higher temporal summation (TS) than CSI<40
- p<0.004
Observational data: associations, not effects.
Further findings
Factors associated with CSI (multivariable linear regression)
- Sex, PCS, IPQ-R Identity, MFIS and HADS anxiety independently associated with CSI; explained variance
- 78%
Original publication
Value of the central sensitisation inventory in patients with axial spondyloarthritis. RMD Open. Published 28 October 2024. doi:10.
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