Spondyloarthritis & psoriatic arthritis
Low Socioeconomic Status and Female Sex are Associated With Worse Functional Status in Axial Spondyloarthritis
Authors' conclusion
In this large sample of patients with axSpA, those with lower SES had worse FS and functional decline. Women had worse FS than men, initially and over time.
Study context
- Population
- Patients with axial spondyloarthritis (axSpA) in the Rheumatology Informatics System for Effectiveness registry2,341 in longitudinal analysis
- Participants
- 5,658 patients
- Exposure
- Area Deprivation Index quintiles and women vs men
- Outcome
- Functional status by MDHAQ (cross-sectional, linear trend across ADI quintiles); functional decline (longitudinal)
Methodological detailsregistry-based (RISE), cross-sectional and longitudinal analyses, generalized estimating equation models
- Registry-based (RISE)
- Cross-sectional and longitudinal analyses
- Generalized estimating equation models
Main finding
As reported in the abstract
Predicted mean MDHAQ score by ADI quintile (cross-sectional)
Lowest Area Deprivation Index (ADI) quintile
2.2
mean · 95% CI 1.8–2.7
Highest ADI quintile
1.8
mean · 95% CI 1.4–2.1
Observational data: associations, not effects.
Further findings
| Outcome | Lowest ADI quintile | Highest ADI quintile | Women | Men | Odds (95% CI) |
|---|---|---|---|---|---|
| MDHAQ score by sex (cross-sectional)Mean | — not stated in the abstract | — not stated in the abstract | 2.1 (SD 2.2) | 1.6 (SD 2.0) | |
| Functional decline by SES quintile (longitudinal) | 14.3% (95% CI 7.6–25.5%) | 9.6% (95% CI 5.2–17.1%) | — not stated in the abstract | — not stated in the abstract | |
| Functional decline by sex (longitudinal)Women vs Men · times higher odds | 1.7 (1.3–2.2) |
— not stated in the abstract
Multidimensional Health Assessment Questionnaire (MDHAQ) score by sex (cross-sectional)
- Women had lower functional status (FSs) compared to men across quintiles
Functional decline by sex (longitudinal)
- No interaction with sex
Original publication
Low Socioeconomic Status and Female Sex are Associated With Worse Functional Status in Axial Spondyloarthritis. Arthritis Care Res (Hoboken). Published 26 October 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →