Spondyloarthritis & psoriatic arthritis
The effect of alcohol consumption on clinical outcomes and structural damage in patients with axial spondyloarthritis: A systematic literature review and meta-analysis
Pooled result · Disease activity (BASDAI)Result — go to the resultSMD −0.19 95% CI −0.37 to −0.02Authors' conclusion
AC appears to be associated with lower disease activity and spinal pain.
Study context
- Population
- Patients with axial spondyloarthritis (axSpA) in observational studies
- Participants
- 3,858 patients5 studies
- Comparison
- Alcohol consumption vs no alcohol consumption in axSpA
- Outcome
- Disease-specific outcomes: spinal pain, disease activity (Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), ASDAS) and spinal radiographic progression (modified Stokes Ankylosing Spondylitis Spinal Score (mSASSS))
Methodological detailsJoanna Briggs Institute Critical Appraisal checklist for risk of bias, SMD synthesis, I2 heterogeneity
- Joanna Briggs Institute Critical Appraisal checklist for risk of bias
- SMD synthesis
- I2 heterogeneity
Pooled result
Disease activity (BASDAI)
SMD
−0.19
95% CI −0.37 to −0.02
Consumersvs Non-consumers
SMD −0.19 (95% CI −0.37 to −0.02)
As reported in the abstract
Further pooled results
| Outcome | SMD (95% CI) | |
|---|---|---|
| Spinal painI2=0% | −0.17 (−0.24 to −0.09) | |
| Spinal radiographic progression (mSASSS)One cohort study · greater radiographic progression among consumers | 0.35 (0.08–0.62) | |
| −0.500.51Difference (linear scale) |
Ankylosing Spondylitis Disease Activity Score (ASDAS)
- No significant difference for ASDAS (SMD: −0.19, 95% CI: −0.39 to 0.00, I2=36%)
Original publication
The effect of alcohol consumption on clinical outcomes and structural damage in patients with axial spondyloarthritis: A systematic literature review and meta-analysis. Joint Bone Spine. Published 24 October 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →