Validation of the parent global assessment as a health-related quality of life measure in juvenile idiopathic arthritis: results from ReACCh-Out
Authors' conclusion
Our results offer support for the parent global as a valid measure of HRQoL for JIA.
Study context
- Population
- Patients with JIA in the Research in Arthritis in Canadian Children emphasizing outcomes (ReACCh-Out) cohort
- Participants
- 344 patients
- Outcome
- Measurement properties (construct validity, responsiveness, reliability) of the parent global assessment as an health-related quality of life (HRQoL) instrument
- Follow-up
- Enrolment and 6 months later
Methodological detailscohort study, prospective cohort (ReACCh-Out), structural equation modelling
- Cohort study
- Prospective cohort (ReACCh-Out)
- Structural equation modelling
Performance
As reported in the abstract
- Spearman correlation with JAQQ, HRQoML, PedsQL-Parent and CHQ-Physical
- 0.53-0.70
- Spearman correlation with PedsQL-Child
- 0.44
- Spearman correlation with CHQ-Psychosocial
- 0.31
- Correlation with disease activity measures (physician global, active joint count, ESR)
- 0.14-0.49
- Responsiveness to improvement by parent ratings (acceptable)
- 0.51
- Responsiveness of other measures
- 0.32-0.71
Further findings
Reliability and measurement error
- Unsatisfactory for all measures, likely due to prolonged time between assessments
Causal pathways (structural equation modelling)
- Causal pathways for the parent global matched those previously reported for HRQoML
Original publication
Validation of the parent global assessment as a health-related quality of life measure in juvenile idiopathic arthritis: results from ReACCh-Out. Rheumatology (Oxford). Published 17 June 2022. doi:10.
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