Lupus & antiphospholipid syndrome
Using patient-reported measures to predict hospitalisation in a population-based lupus cohort
Authors' conclusion
This study suggests that patient-reported SLE symptoms and disease activity, specifically certain components of the SLAQ, may be of value in SLE risk management when considering hospitalisation reduction as a treatment goal.
Study context
- Population
- Population-based SLE cohort (Georgians Organized Against Lupus (GOAL)), Georgia, 2011 to 2013, with yearly self-report surveys (Systemic Lupus Activity Questionnaire (SLAQ)) linked to the Georgia Hospital Discharge Database1,486 surveys
- Participants
- 846 participants
- Exposure
- Weight loss + severe fatigue + Raynaud's subset vs Overall GOAL vs Lowest-rate subset
- Outcome
- All-cause hospitalisation
- Follow-up
- 6 months following survey completion
Methodological detailsobservational, population-based, logistic regression and classification and regression tree (CART) models
- Observational
- Population-based
- Logistic regression and classification and regression tree (CART) models
Main finding
As reported in the abstract
All-cause hospitalisation rate by CART subset
Fold rate
2.6
Weight loss + severe fatigue + Raynaud's subset vs Overall GOAL
Fold rate
6.8
Weight loss + severe fatigue + Raynaud's subset vs Lowest-rate subset
Observational data: associations, not effects.
Further findings
Characteristics of hospitalised vs non-hospitalised participants · 6 months after survey completion
- Hospitalised participants more likely younger, living in poverty and with more reported SLE symptoms
Original publication
Using patient-reported measures to predict hospitalisation in a population-based lupus cohort. Lupus Sci Med. Published 23 March 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →