Spondyloarthritis & psoriatic arthritis
Use of the Bath Ankylosing Spondylitis Disease Activity Index in Patients With Psoriatic Arthritis With and Without Axial Disease
Authors' conclusion
BASDAI has reasonable responsiveness in PsA but does not differentiate between axPsA and peripheral PsA.
Study context
- Population
- Individuals with psoriatic arthritis (PsA) initiating therapy in a longitudinal cohort study based in the United States
- Participants
- 40 vs 79
- Exposure
- Axial PsA vs peripheral-only PsA
- Axial PsA (axPsA)n = 40
- Peripheral-onlyn = 79reference
- Outcome
- Responsiveness of BASDAI (SRM: mean change divided by SD of the change) and differentiation between axial and peripheral disease activity
Methodological detailslongitudinal cohort, United States
- Longitudinal cohort
- United States
Main finding
As reported in the abstract
BASDAI responsiveness: mean change after therapy initiation
axPsA
−0.75
mean
Peripheral-only
−0.83
mean
- SRM for Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), axial vs peripheral disease
- −0.37 vs −0.44
Observational data: associations, not effects.
Further findings
Mean
| Outcome | axPsA | Peripheral-only |
|---|---|---|
| Baseline BASDAI score · therapy initiation | 5.0 (SD 2.2) | 4.8 (SD 2.0) |
Baseline BASDAI score · therapy initiation
- No significant difference in patient-reported outcome scores between the groups
Original publication
Use of the Bath Ankylosing Spondylitis Disease Activity Index in Patients With Psoriatic Arthritis With and Without Axial Disease. J Rheumatol. Published 15 December 2023. doi:10.
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