Spondyloarthritis & psoriatic arthritis

Sensitivity and Specificity of Composite Indices of Remission in Male and Female Patients With Psoriatic Arthritis: A Multicenter Cross-Sectional Study of Longitudinal Cohorts

J RheumatolPublished Cross-sectional study

Authors' conclusion

The results of this study demonstrate for the first time, to our knowledge, that some differences between the 2 sexes on the different outcome indices are possible.

Study context

Population
Patients with PsA consecutively attending rheumatology units, 2 longitudinal cohorts (mean age 55.7 [SD 12.4])
Participants
272 patients
Exposure
Male vs female patients with PsA: Minimal disease activity (MDA), DAPSA and Psoriatic Arthritis Impact of Disease (PsAID) vs clinical remission (physician and patient perspective)
  • Malen = 141
  • Femalen = 131
Outcome
Sex differences in sensitivity, specificity, PPV, NPV and likelihood ratio of MDA, DAPSA and PsAID vs clinical remission (PGA ≤ 1, physician and patient perspective)
Methodological detailsmulticentre, cross-sectional analysis of 2 longitudinal cohorts, consecutive patients
  • Multicentre
  • Cross-sectional analysis of 2 longitudinal cohorts
  • Consecutive patients

Main finding

As reported in the abstract

DAPSA remission (≤ 4) vs physician-judged remission
GroupSensitivitySpecificity
Female45.4%100%
Male33.3%84.2%

Sensitivity

Female45.4%
Male33.3%

Specificity

Female100%
Male84.2%

Observational data: associations, not effects.

Original publication

Sensitivity and Specificity of Composite Indices of Remission in Male and Female Patients With Psoriatic Arthritis: A Multicenter Cross-Sectional Study of Longitudinal Cohorts. J Rheumatol. Published 15 December 2023. doi:10.3899/jrheum.2023-0786

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