Spondyloarthritis & psoriatic arthritis
Sensitivity and Specificity of Composite Indices of Remission in Male and Female Patients With Psoriatic Arthritis: A Multicenter Cross-Sectional Study of Longitudinal Cohorts
Authors' conclusion
The results of this study demonstrate for the first time, to our knowledge, that some differences between the 2 sexes on the different outcome indices are possible.
Study context
- Population
- Patients with PsA consecutively attending rheumatology units, 2 longitudinal cohorts (mean age 55.7 [SD 12.4])
- Participants
- 272 patients
- Exposure
- Male vs female patients with PsA: Minimal disease activity (MDA), DAPSA and Psoriatic Arthritis Impact of Disease (PsAID) vs clinical remission (physician and patient perspective)
- Malen = 141
- Femalen = 131
- Outcome
- Sex differences in sensitivity, specificity, PPV, NPV and likelihood ratio of MDA, DAPSA and PsAID vs clinical remission (PGA ≤ 1, physician and patient perspective)
Methodological detailsmulticentre, cross-sectional analysis of 2 longitudinal cohorts, consecutive patients
- Multicentre
- Cross-sectional analysis of 2 longitudinal cohorts
- Consecutive patients
Main finding
As reported in the abstract
DAPSA remission (≤ 4) vs physician-judged remission
| Group | Sensitivity | Specificity |
|---|---|---|
| Female | 45.4% | 100% |
| Male | 33.3% | 84.2% |
Sensitivity
Female45.4%
Male33.3%
Specificity
Female100%
Male84.2%
Observational data: associations, not effects.
Original publication
Sensitivity and Specificity of Composite Indices of Remission in Male and Female Patients With Psoriatic Arthritis: A Multicenter Cross-Sectional Study of Longitudinal Cohorts. J Rheumatol. Published 15 December 2023. doi:10. 3899/ jrheum. 2023-0786
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