Systemic sclerosis & Raynaud's

Ultrasound quantitative assessment of ventral finger microvasculopathy in systemic sclerosis with Raynaud’s phenomena: a comparative study

RMD OpenPublished Comparative diagnostic study

Authors' conclusion

Ultrasound demonstrated potential to quantify finger vascularity of RP-SSc. The ventral side of the fingers showed a higher accuracy in detecting RP-SSc than the dorsal side.

Study context

Population
SSc patients with RP and controls; all fingers (except thumbs) imaged at room temperature
Participants
18 vs 18
Comparison
RP-SSc patients vs controls
  • RP-SScn = 18
  • Controlsn = 18reference
Outcome
Finger vascularity by US: percent vascular area and mean vascular intensity, dorsal (nail fold) and ventral (fingertip) sides
Methodological detailscase-control, four ultrasound vascular imaging techniques
  • Case-control
  • Four ultrasound vascular imaging techniques

Performance

As reported in the abstract

Percent vascular area and mean vascular intensity, dorsal and ventral sides

AUC, mean vascular intensities vs percent vascular areas (regardless of technique and side)

0.53-0.91 vs 0.53-0.90

AUC, ventral side vascularity

0.74-0.91

AUC, dorsal side vascularity

0.53-0.81

Further findings

Ventral side abnormalities were associated with a history of digital ulcers

Original publication

Ultrasound quantitative assessment of ventral finger microvasculopathy in systemic sclerosis with Raynaud’s phenomena: a comparative study. RMD Open. Published 14 February 2023. doi:10.1136/rmdopen-2022-002954

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