Systemic sclerosis & Raynaud's
Ultrasound quantitative assessment of ventral finger microvasculopathy in systemic sclerosis with Raynaud’s phenomena: a comparative study
Authors' conclusion
Ultrasound demonstrated potential to quantify finger vascularity of RP-SSc. The ventral side of the fingers showed a higher accuracy in detecting RP-SSc than the dorsal side.
Study context
- Population
- SSc patients with RP and controls; all fingers (except thumbs) imaged at room temperature
- Participants
- 18 vs 18
- Comparison
- RP-SSc patients vs controls
- RP-SScn = 18
- Controlsn = 18reference
- Outcome
- Finger vascularity by US: percent vascular area and mean vascular intensity, dorsal (nail fold) and ventral (fingertip) sides
Methodological detailscase-control, four ultrasound vascular imaging techniques
- Case-control
- Four ultrasound vascular imaging techniques
Performance
As reported in the abstract
Percent vascular area and mean vascular intensity, dorsal and ventral sides
AUC, mean vascular intensities vs percent vascular areas (regardless of technique and side)
0.53-0.91 vs 0.53-0.90
AUC, ventral side vascularity
0.74-0.91
AUC, dorsal side vascularity
0.53-0.81
Further findings
- Ventral side abnormalities were associated with a history of digital ulcers
Original publication
Ultrasound quantitative assessment of ventral finger microvasculopathy in systemic sclerosis with Raynaud’s phenomena: a comparative study. RMD Open. Published 14 February 2023. doi:10. 1136/ rmdopen-2022-002954
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