Systemic sclerosis & Raynaud's
Reporting and Representativeness of Race, Ethnicity, and Socioeconomic Status in Systemic Sclerosis Randomized Trials: An Observational Study
Authors' conclusion
Documentation of race/ethnicity and socioeconomic status is poor in RCTs on SSc.
Study context
- Population
- Published randomized controlled trials (RCTs) on systemic sclerosis (SSc) indexed in PubMed, from 2000 onward
- Participants
- 6,693 participants106 studies
- Outcome
- Reporting of race/ethnicity and socioeconomic status of participants in SSc RCTs, and representativeness of ethnic/racial groups
Methodological detailsobservational study, multivariable logistic regression, comparison with US demographic data, Studies mostly conducted in Europe (42%) or North America (25%), published after 2010 (74%)
- Observational study
- Multivariable logistic regression
- Comparison with US demographic data
- Studies mostly conducted in Europe (42%) or North America (25%), published after 2010 (74%)
Pooled result
As reported in the abstract
- Papers reporting patients' socioeconomic status
- 2
Further pooled results
Representation of racial/ethnic groups in studies reporting race/ethnicity
- White
- 79%
- Asian
- 7%
- African American
- 6%
Representation of African American patients in US studies (sensitivity analysis)
- Underrepresentation of African American patients in 2000-2010, but not later
- Sensitivity analysis limited to studies from the US
Original publication
Reporting and Representativeness of Race, Ethnicity, and Socioeconomic Status in Systemic Sclerosis Randomized Trials: An Observational Study. Arthritis Care Res (Hoboken). Published 13 February 2023. doi:10. 1002/ acr. 25059
Composed by AI from the published abstract and checked against it. How Briefs are made →