Systemic sclerosis & Raynaud's
Impact of Season, Environmental Temperature, and Humidity on Raynaud Phenomenon in an Australian Systemic Sclerosis Cohort
Authors' conclusion
Lower environmental temperature and higher relative humidity had significant associations with worsened RP in this systemic sclerosis cohort
Study context
- Population
- Patients with SSc in the Australian Scleroderma Cohort Study; mean monthly weather data from the closest weather station to the patient's address
- Participants
- 1,972 patients9,175 visits
- Outcome
- Patient-reported worsened RP in the month preceding each study visit
- Follow-up
- Preceding month
Methodological detailsmultivariable analysis
- Multivariable analysis
Main finding
As reported in the abstract
Worsened RP, multivariable associations with weather
Odds ratio (95% CI)P value
Low mean maximum temperatures
0.91(0.90–0.92)
P < 0.001High relative humidity
1.05(1.04–1.05)
P < 0.001Lower mean daily evaporation
0.77(0.73–0.81)
P < 0.001- Worsened Raynaud phenomenon (RP) in the preceding month reported
- 26.7%
Observational data: associations, not effects.
Further findings
Clinical associations of worsened RP
- Strongly associated with telangiectasia, calcinosis and digital ulceration
- Associated with anticentromere antibody and gastroesophageal reflux disease
- Negative correlation with diffuse disease
Health-related quality of life (HRQoL) (Short Form 36)
- Worsened RP strongly associated with worse HRQoL
Original publication
Impact of Season, Environmental Temperature, and Humidity on Raynaud Phenomenon in an Australian Systemic Sclerosis Cohort. Arthritis Care Res (Hoboken). Published 10 November 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →