Ultrasound-detected tenosynovitis in ankles with clinical arthritis and short-term outcome of patients with new-onset juvenile idiopathic arthritis
Main finding · Clinically inactive diseaseResult — go to the resultHazard ratio 1.12 95% CI 0.51–2.45Authors' conclusion
US-detected tenosynovitis is frequent in ankles with clinical arthritis at JIA onset but does not impair the chance of achieving clinically inactive disease in the early disease phase.
Study context
- Population
- Children with new-onset juvenile idiopathic arthritis (JIA) and clinically active disease of the ankle
- Participants
- 45 children
- Exposure
- Ultrasound (US)-detected tenosynovitis vs isolated arthritis of the ankle
- Tenosynovitisn = 28
- Isolated arthritisn = 17reference
- Outcome
- Achievement of clinically inactive disease
- Follow-up
- 6 months after starting treatment
Methodological detailsKaplan-Meier method, Cox model
- Kaplan-Meier method
- Cox model
Main finding
Clinically inactive disease · 6 months
Hazard ratio
1.12
95% CI 0.51–2.45
By group
Tenosynovitisvs Isolated arthritis
HR 1.12 (95% CI 0.51–2.45)
As reported in the abstract
Observational data: associations, not effects.
Further findings
Frequency of US-detected ankle tenosynovitis
| Outcome | Tenosynovitis | Isolated arthritis | HR (95% CI) | |
|---|---|---|---|---|
| Clinically inactive disease, excluding patients given biologics (subanalysis) | 64.7% | 54.5% | 1.56 (0.58–4.24) | |
| 0.20.5125Hazard ratio (log scale) |
Frequency of US-detected ankle tenosynovitis
- Medial and lateral tendon compartments most frequently inflamed
US reliability (kappa)
- The rate of US reliability was high
Original publication
Ultrasound-detected tenosynovitis in ankles with clinical arthritis and short-term outcome of patients with new-onset juvenile idiopathic arthritis. Clin Exp Rheumatol. Published 20 November 2023. doi:10.
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