Sjögren's disease & overlap diseases
Ultrasonographic scores and parotid histopathology in Sjögren's disease: challenges in lymphoma identification
Authors' conclusion
The current SGUS scores seem not to allow identifying lymphoma in SjD patients with high clinical suspicion.
Study context
- Population
- Consecutive adult Sjögren's disease (SjD) patients with a clinical indication for parotid gland biopsy, September 2018 to October 202324 (42%) with lymphoma
- Participants
- 57 patients
- Comparison
- OMERACT vs Hocevar et al. Salivary gland ultrasound (SGUS) scores for identifying lymphoma
- Outcome
- Identification of lymphoma (parotid histopathology) by SGUS scores
Methodological detailsconsecutive patients
- Consecutive patients
Performance
As reported in the abstract
Association of SGUS score with lymphoma
| Test or model | OR | 95% CI | p |
|---|---|---|---|
| OMERACT | 1.10 | 0.91-1.34 | p=0.305 |
| Hocevar et al. | 1.03 | 0.97-1.10 | p=0.300 |
OR
OMERACT1.10
Hocevar et al.1.03
95% CI
OMERACT0.91-1.34
Hocevar et al.0.97-1.10
p
OMERACTp=0.305
Hocevar et al.p=0.300
Further findings
| Outcome | OMERACT | Hocevar et al. |
|---|---|---|
| LELs vs SGUS scores (33 patients without lymphoma), regression | ||
| β | 3.57 | 8.16 |
| 95% CI | 1.53-5.61 | 1.45-14.87 |
| p | p=0.001 | p=0.019 |
| FS vs SGUS scores (33 patients without lymphoma), regression | ||
| β | 0.26 | 0.57 |
| 95% CI | 0.09-0.43 | 0.03-1.12 |
| p | p=0.004 | p=0.040 |
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Ultrasonographic scores and parotid histopathology in Sjögren's disease: challenges in lymphoma identification. Clin Exp Rheumatol. Published 2 October 2024. doi:10.
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