Lupus & antiphospholipid syndrome
Ultrasonographic assessment of optic nerve: does it help in lupus-induced optic neuropathy?
Authors' conclusion
Ultrasonographic evaluation of the optic nerve may add significant value to the diagnosis of optic neuropathy in patients with SLE and should be considered a complementary tool to other conventional methods.
Study context
- Population
- Patients with systemic lupus erythematosus (SLE) and healthy controls
- Participants
- 140 patients
- Exposure
- SLE vs healthy controls
- SLEn = 65
- Controlsn = 75reference
- Outcome
- Optic nerve diameter (OND) and optic nerve sheath diameter (ONSD) on neuromuscular ultrasonography (NMUS)
Methodological detailsobservational
- Observational
Main finding
As reported in the abstract
- SLE vs Controls: P = 0.017
- SLE vs Controls: 0.004
Observational data: associations, not effects.
Further findings
Diagnostic performance of optic nerve US in SLE vs ophthalmological evaluation and visual evoked potential (VEP)
- Very low sensitivity
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Ultrasonographic assessment of optic nerve: does it help in lupus-induced optic neuropathy? Lupus Sci Med. Published 20 January 2025. doi:10.
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