Trends in the occurrence of ischaemic heart disease over time in rheumatoid arthritis: 1821 patients from 1972 to 2017
Authors' conclusion
Incidence rates and excess events of AMI and IHD in RA patients declined from 1972 to 2017. There were no excess AMI or IHD events in RA patients diagnosed after 1998 compared with the general population.
Study context
- Population
- Rheumatoid arthritis (RA) patients diagnosed 1972–2013, Hordaland, Norway
- Participants
- 1,821 patients
- Exposure
- RA patients vs the general population
- RAn = 1,821
- Outcome
- Trends in AMI and IHD incidence rates and excess events (standardized event ratio (SER)) vs the general population over time
Methodological detailsPoisson regression, general-population comparison (Hordaland, Norway)
- Poisson regression
- General-population comparison (Hordaland, Norway)
Main finding
As reported in the abstract
Trends in AMI and IHD incidence and excess events · 1972–2017
Average annual decline in age- and gender-adjusted acute myocardial infarction (AMI) incidence rates, 1972–2017 (p < 0.035)
1.6%
Average annual decline in excess AMI events in RA vs general population, 1972–2014
1.3%
Average annual decline in excess ischaemic heart disease (IHD) events in RA vs general population, 1972–2014
2.3%
Observational data: associations, not effects.
Further findings
| Outcome | SER (95% CI) |
|---|---|
| Excess AMI events, RA diagnosed after 1998 (subgroup)Not significant | 1.05 (0.82–1.35) |
| Excess IHD events, RA diagnosed after 1998 (subgroup)Not significant | 1.02 (0.89–1.16) |
Original publication
Trends in the occurrence of ischaemic heart disease over time in rheumatoid arthritis: 1821 patients from 1972 to 2017. Scand J Rheumatol. Published 11 March 2022. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →