Rheumatoid arthritis

Diagnosis of COVID-19 associated arthritis in patients with or without underlying rheumatic and musculoskeletal disease supported by musculoskeletal ultrasound: a case series from three European centres

Clin Exp RheumatolPublished Case series

Authors' conclusion

In our patients without underlying RMD, arthritides associated with COVID-19 are comparable to the clinical picture of a reactive arthritis (ReA) or other virus-related arthritides (e.g. parvovirus B19). New onset or flares of RMD possibly triggered by COVID-19 are noteworthy.

Study context

Population
Adults with arthritis timely related to COVID-19, assessed clinically, by laboratory values and musculoskeletal ultrasound (MSUS), three European centres, March 2020 to July 2021
Participants
10 adults
Exposure
Without underlying rheumatic and musculoskeletal disease (RMD) vs With underlying RMD
  • Without underlying RMDn = 6
  • With underlying RMDn = 4
Outcome
Forms of COVID-19 associated arthritis (clinical and MSUS)
Methodological detailsmulticentre, three European centres
  • Multicentre
  • Three European centres

Main finding

As reported in the abstract

Without RMD: polyarticular arthralgia during severe COVID-19, swelling rarely seen, MSUS arthritis only in a few joints affected
2
Without RMD: arthritis four to 16 weeks after mild or moderate COVID-19 (without hospitalisation)
4
Without RMD: polyarthritis
1
Without RMD: oligoarthritis of the upper and lower limb
2
Without RMD: late-onset RA newly diagnosed
1
With RMD: increase of disease activity by MSUS during mild and mild-moderate COVID-19
4

Observational data: associations, not effects.

Original publication

Diagnosis of COVID-19 associated arthritis in patients with or without underlying rheumatic and musculoskeletal disease supported by musculoskeletal ultrasound: a case series from three European centres. Clin Exp Rheumatol. Published 2 March 2022. doi:10.55563/clinexprheumatol/an1yrh

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