Trends in Prevalence of Gout Among US Asian Adults, 2011-2018
Authors' conclusion
The findings of this study suggest that the prevalence of gout among Asian individuals numerically surpassed that for all other racial and ethnic groups in 2017 to 2018. This Asian vs White disparity did not appear to be associated with socioclinical factors.
Study context
- Population
- Nationally representative sample of US adults, National Health and Nutrition Examination Survey (NHANES) 2011–2018; replication in UK Biobank (2006–2021)NHANES 2011–2018
- Participants
- 22,621 participants
- Exposure
- Gout prevalence and serum urate by race and ethnicity; Asian vs White individuals
- Outcome
- Race-specific gout prevalence and serum urate levels
Methodological detailspopulation-based, nationally representative sample, replication in UK Biobank
- Population-based
- Nationally representative sample
- Replication in UK Biobank
Main finding
As reported in the abstract
Age- and sex-adjusted gout prevalence among Asian Americans · 2011 to 2012 vs 2017 to 2018
Each group vs whiteEstimate (95% CI)
Asian
age- and sex-adjusted OR 1.61(1.03–2.51)
Asian
socioclinical factor-adjusted multivariable OR 2.62(1.59–4.33)
- Asian Americans, 2011 to 2012
- 3.3% (95% CI, 2.1%-4.5%)
- Asian Americans, 2017 to 2018 (95% CI, 4.4%-8.8%); P for trend = .007
- 6.6%
Observational data: associations, not effects.
Further findings
Age- and sex-adjusted gout prevalence, aged 65 years and older (latest)
Asian men Asian 23.6%
Crude gout prevalence, all US adults · 2011 to 2012 vs 2017 to 2018
- 2011 to 2012
- 3.6% (95% CI, 2.8%-4.5%)
- 2017 to 2018 (95% CI, 4.2%-5.9%); P for trend = .03
- 5.1%
- US individuals affected by gout, 2017 to 2018
- 12.1 million
- Trend after age adjustment
- P for trend = 0.06
- Trend excluding Asian individuals
- P for trend = 0.11
Serum urate concentrations among US Asian individuals · 2011 to 2018
- Increased between 2011 and 2018
- P for trend = 0.009
Asian vs White disparity in UK Biobank
- Asian vs White disparity also present
Original publication
Trends in Prevalence of Gout Among US Asian Adults, 2011-2018. JAMA Netw Open. Published 3 April 2023. doi:10.
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