Prevalence of and trends in hyperuricemia by race and ethnicity among US adolescents, 1999–2018
Authors' conclusion
Our results suggest that hyperuricemia has a significant association with greater obesity in US adolescents, and the degree of correlation varies by sex and race/ethnicity.
Study context
- Population
- US adolescents aged 12–17 years, NHANES 1999–2018; hyperuricemia defined as ≥ 5.5 mg/dL
- Participants
- 11,264 adolescents
- Exposure
- Males vs Females
- Outcome
- Prevalence of hyperuricemia and trends
- Follow-up
- 2015-2018
Methodological detailsNHANES 1999-2018, four-year survey cycles, linear, logistic and Poisson regression
- NHANES 1999-2018
- Four-year survey cycles
- Linear, logistic and Poisson regression
Main finding
As reported in the abstract
Hyperuricemia prevalence
- Overall hyperuricemia prevalence
- 32.78%
Observational data: associations, not effects.
Further findings
| Outcome | PR (95% CI) | |
|---|---|---|
| Factors associated with hyperuricemia · 2011-2018Malesvs Females | 3.50 (2.83–4.33) | |
| Factors associated with hyperuricemia · 2011-2018Non-Hispanic Asiansvs Non-Hispanic Whites | 1.26 (1.04–1.53) | |
| Factors associated with hyperuricemia · 2011-2018Overweightvs Normal weight | 1.63 (1.32–2.01) | |
| Factors associated with hyperuricemia · 2011-2018Obesityvs Normal weight | 2.45 (2.08–2.88) | |
| 0.20.5125Prevalence ratio (log scale) |
Obesity and hyperuricemia, by sex (subgroup) · 2011-2018
| PR (95% CI) | ||
|---|---|---|
| Obesity (females) | 4.77 (3.08–7.39) | |
| Obesity (males) | 2.06 (1.82–2.34) | |
| 0.10.31310Prevalence ratio (log scale) |
Obesity and hyperuricemia, non-Hispanic Black adolescents (subgroup) · 2011-2018
| PR (95% CI) | ||
|---|---|---|
| Obesity (non-Hispanic Black)Higher PRs in comparison to other ethnic groups | 3.40 (2.54–4.55) | |
| 0.20.5125Prevalence ratio (log scale) |
Original publication
Prevalence of and trends in hyperuricemia by race and ethnicity among US adolescents, 1999–2018. Arthritis Res Ther. Published 8 November 2024. doi:10.
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