Effectiveness and safety of bisphosphonates in inflammatory bone disorders: a systematic review
Authors' conclusion
Bisphosphonate therapy, particularly pamidronate, is effective and well tolerated in children with IBDs, particularly when combined with other treatments.
Study context
- Population
- Children with inflammatory bone disorders (IBDs) treated with bisphosphonates; articles published January 2000–July 202426 articles
- Participants
- 895 children
- Outcome
- Clinical and radiological remission and safety
Methodological detailsPRISMA 2020, Study quality assessed with the NIH quality assessment tools for observational studies
- PRISMA 2020
- Study quality assessed with the NIH quality assessment tools for observational studies
Pooled result
As reported in the abstract
Remission, symptoms and radiological outcomes with pamidronate
- Pamidronate: significant improvements in remission rates, symptom reduction and radiological outcomes
Original publication
Effectiveness and safety of bisphosphonates in inflammatory bone disorders: a systematic review. Clin Exp Rheumatol. Published 5 November 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →