Vasculitis & polymyalgia rheumatica
Traditional and disease-related cardiovascular risk factors in ANCA-associated vasculitis: A prospective, two-centre cohort study
Authors' conclusion
Determinants of an increased CV risk were identified.
Study context
- Population
- Patients with ANCA-associated vasculitis (AAV) recruited from centres in the Netherlands and Canada
- Participants
- 144 patients
- Outcome
- First CV event, related to baseline traditional and disease-related CV risk determinants
Methodological detailstwo-centre, Cox proportional hazards analyses
- Two-centre
- Cox proportional hazards analyses
Main finding
As reported in the abstract
CV events · median follow-up 2.90 years
Patients with a cardiovascular (CV) event (14 non-fatal, 2 fatal)
16
11%
Incidence of CV events per 100 patient-years
5.45
Observational data: associations, not effects.
Further findings
Insulin resistance at inclusion (patients tested)
- Insulin resistance present, independent of concurrent prednisone therapy
- 73%
Original publication
Traditional and disease-related cardiovascular risk factors in ANCA-associated vasculitis: A prospective, two-centre cohort study. Joint Bone Spine. Published 8 February 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →