The performance of the 2019 European League Against Rheumatism (EULAR)/American College of Rheumatology (ACR) classification criteria in childhood-onset systemic lupus erythematosus
Authors' conclusion
The 2019 EULAR/ACR criteria classified patients with higher sensitivity at diagnosis and at the first-year follow-up. However, 2019 EULAR/ACR criteria at last visit demonstrated an equal sensitivity to 2012 SLICC. The specificity performance of 2019 EULAR/ACR could not reach to the level of 1997 ACR, but it was more successful than 2012 SLICC.
Study context
- Population
- Patients with childhood-onset systemic lupus erythematosus (SLE) (cSLE)82% female
- Participants
- 111 patients
- Comparison
- 2019 EULAR/ACR vs 1997 ACR vs 2012 Systemic Lupus International Collaborating Clinics (SLICC) classification criteria
- Outcome
- Sensitivity and specificity of the classification criteria
- Follow-up
- At diagnosis
Methodological detailslongitudinal
- Longitudinal
Performance
As reported in the abstract
Sensitivity
| Test or model | Sensitivity |
|---|---|
| 2019 EULAR/ACR | 93.7% |
2019 EULAR/ACR
Sensitivity93.7%
- 2019 EULAR/ACR had the highest sensitivity at diagnosis
- 93.7%
Further findings
Sensitivity · last visit
Sensitivity
Specificity
Specificity
| Outcome | 2019 EULAR/ACR | 1997 ACR | 2012 SLICC |
|---|---|---|---|
| Sensitivity · first-year follow-up | |||
| Sensitivity | 96% | — not stated in the abstract | — not stated in the abstract |
— not stated in the abstract
- Sensitivity — 2019 EULAR/ACR had the highest sensitivity at first-year follow-up
- 96%
Specificity
- Difference not significant
Original publication
The performance of the 2019 EULAR/ACR classification criteria in childhood-onset systemic lupus erythematosus. Lupus. Published 4 March 2025. doi:10.
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