Illness perception and psychological distress in adolescents with systemic lupus erythematosus
Authors' conclusion
Psychological distress including depressive symptoms, anxiety, fatigue, pain, and sleep quality significantly correlated to illness perception in adolescent SLE.
Study context
- Population
- Adolescents aged 12–18 years diagnosed with Systemic Lupus Erythematosus (SLE), assessed during a clinic visit94.1% female
- Participants
- 102 adolescents
- Outcome
- Relationships between illness perception (B-IPQ) and depressive symptoms, anxiety, fatigue, pain and sleep quality; factors associated with negative illness perception
Methodological detailsmultivariable regression analysis
- Multivariable regression analysis
Main finding
As reported in the abstract
- Depressive symptoms (moderate correlation), r
- 0.487
- Anxiety (moderate correlation), r
- 0.459
- Fatigue (moderate correlation), r
- 0.493
- Pain (weak correlation), r
- 0.334
- Sleep quality (weak correlation), r
- 0.355
- Physician Global Assessment (PGA) (weak correlation), r
- 0.255
Observational data: associations, not effects.
Further findings
Factors associated with negative illness perception (multivariable regression)
| B coefficient (95% CI) | P value | |
|---|---|---|
| Self-reported poor relationship with friends | 9.12 (3.22–15.01) | P = 0.003 |
| PGA score ≥0.5 | 8.61 (3.52–13.69) | P = 0.001 |
Prevalence of psychological issues
- Depressive symptoms (Patient Health Questionnaire for Adolescents (PHQ-A) ≥5)
- 31.4%
- Anxiety (GAD-7 ≥7)
- 14.7%
- Pain (Visual Analogue Scale of Pain (VAS-P) > 3)
- 14.7%
- Poor sleep quality (Pittsburgh Sleep Quality Index (PSQI)>5)
- 29.4%
Brief Illness Perception Questionnaire (B-IPQ) items
- Timeline perceived most negatively; treatment control most positively
Original publication
Illness perception and psychological distress in adolescents with systemic lupus erythematosus. Lupus. Published 2 March 2025. doi:10.
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