The impact of psoriasis on wellbeing and clinical outcomes in juvenile psoriatic arthritis
Authors' conclusion
CYP with psoriasis at JPsA diagnosis report worse mood, supporting a greater disease impact in those with both skin and joint involvement.
Study context
- Population
- Children and young people recruited to the Childhood Arthritis Prospective Study, a UK multicentre JIA inception cohort, January 2001–March 2018
- Exposure
- Juvenile PsA (JPsA) vs other JIA categories; within JPsA, with vs without psoriasis
- Outcome
- Patient-reported outcomes at diagnosis and 3-year outcome trajectories (active joint counts, PGA, PaGA)
Methodological detailsinception cohort, multicentre, multivariable linear regression
- Inception cohort
- Multicentre
- Multivariable linear regression
Main finding
As reported in the abstract
Coefficient
9.8
95% CI 0.5–19.0
JPsA with psoriasis vs JPsA without psoriasis · depressive symptoms at diagnosis
Odds
2.3
95% CI 1.2–4.6
JPsA vs Non-JPsA · persistent high PaGA trajectory, despite improving joint counts and PGA
Observational data: associations, not effects.
Original publication
The impact of psoriasis on wellbeing and clinical outcomes in juvenile psoriatic arthritis. Rheumatology (Oxford). Published 19 July 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →