Evaluation of synovial inflammation in juvenile idiopathic arthritis using superb microvascular imaging compared with power Doppler ultrasound
Authors' conclusion
SMI may detect the synovial inflammation with greater sensitivity than PDUS in patients with JIA, and correlate well with the inflammatory biomarkers.
Study context
- Population
- Patients with juvenile idiopathic arthritis (JIA): 59 with active disease and 62 with inactive disease59 active, 62 inactive
- Comparison
- Superb microvascular imaging (SMI) vs power Doppler ultrasound (PDUS) for evaluating synovial inflammation
- Outcome
- Vascularity index of synovial inflammation
Methodological detailsSpearman's correlation, ROC curve analysis
- Spearman's correlation
- ROC curve analysis
Performance
As reported in the abstract
- SMI vascularity index (VI) significantly higher than PDUS VI in JIA patients regardless of disease activity
Further findings
Correlation of VI with inflammatory biomarkers
- SMI and PDUS VI significantly correlated with erythrocyte sedimentation rate (ESR), C-reactive protein (CRP) and serum amyloid A (SAA)
Relapse prediction in inactive disease
- SMI VI significantly higher in relapse than in remission
- SMI showed superior performance in predicting relapse in JIA with inactive disease
Original publication
Evaluation of synovial inflammation in juvenile idiopathic arthritis using superb microvascular imaging compared with power Doppler ultrasound. Clin Exp Rheumatol. Published 17 July 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →